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Description:The primary objective of the Institute of Pharmacology and Structural Biology is the identification, characterization and exploitation of novel therapeutic targets in the fields of Cancer, Infection...

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Ip Country: France
City Name: Paris
Latitude: 48.8323
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EN FR Jobs Opportunities IPBS-Toulouse Research Core Facilities International Training About the IPBS Research Core Facilities International Training About the IPBS Home IPBS Toulouse Better understanding towards better therapeutics in Cancer, Infection and Inflammation. News Jean-Philippe Girard receives the Grand Prix Oberling-Haguenau from the ARC Foundation Tumor-associated HEVs (TA-HEVs) function as portals of entry for lymphocytes into tumors during cancer immunotherapy. Multiphoton imaging of lymphocytes (in Read More » 18 April 2024 Press releases Respiratory allergies: newly discovered molecule plays a major role in triggering inflammation • Inflammation plays a major role in allergic diseases, affecting at least 17 million people in France, including 4 million Read More » 10 April 2024 News Wendy Le Mouëllic, finalist in the Ma thèse en 180 secondes” competition Ma thèse en 180 secondes” enables doctoral students to present their research topic, in French and in simple terms, to Read More » 30 March 2024 News Official launch of the Franco-Indian International Research Network MIRA: Toulouse delegation’s visit in India from March 5 to 7, 2024 As part of the international research network (IRN) MIRA (Emerging Infectious Diseases and Antibiotic Resistance) , a Toulouse delegation composed Read More » 13 March 2024 See all news Agenda Tuesday 21 May, 11:00 Dr. Hung Le - Hunt to eat: metabolic reprogramming drives the dynamics of interbacterial predation IPBS-Toulouse, Seminar room 27 - 31 May Analyses protéomiques quantitatives : Choix de méthodes et analyse des données Centre de vacances du Lazaret Tuesday 28 May, 11:00 Dr. Thomas Marichal - Regulation of monocyte-to-macrophage trajectories in the healthy and diseased lung IPBS-Toulouse, Seminar room Tuesday 11 June, 11:00 Dr. Salvatore Spicuglia - Dissection of cis-regulatory elements in normal and pathological conditions IPBS-Toulouse, Seminar room See all events Featured publications (2023-2024) Schmitt*, Duval* et al. (2024) TL1A is an epithelial alarmin that cooperates with IL-33 for initiation of allergic airway inflammation . J Exp Med 221 (6): e20231236 Rozario*, Pinilla* et al. (2024) Mechanistic basis for potassium efflux–driven activation of the human NLRP1 inflammasome . Proc Natl Acad Sci USA 121 (2) e2309579121 Kougkolos et al . (2024) Skin electroporation for transdermal drug delivery: Electrical measurements, numerical model and molecule delivery . J Control Release 367:235-247 Mascarau et al. (2023) Productive HIV-1 infection of tissue macrophages by fusion with infected CD4+ T cells . J Cell Biol 222:e202205103 Viljoen*, Vercellone* et al. (2023) Nanoscale clustering of mycobacterial ligands and DC-SIGN host receptors are key determinants for pathogen recognition . Sci Adv 9(20):eadf9498 Seif-El-Dahan*, Kefala-Stavridi*, Frit*, Hardwick* et al . (2023) PAXX binding to the NHEJ machinery explains functional redundancy with XLF . Sci Adv 9(22):eadg2834 Kefala-Stavridi*, Gontier*, Morin*, Frit* et al . (2023) Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction . Nucleic Acids Res Oct 23:gkad863 Pinilla et al. (2023) EEF2-inactivating toxins engage the NLRP1 inflammasome and promote epithelial barrier disruption . J Exp Med 220(10):e20230104 About the IPBS The IPBS is a joint research center of the CNRS and the University of Toulouse. Occupying 12,000 m2 in the heart of the main campus of the University of Toulouse III-Paul Sabatier, which offers high-level multidisciplinary training in the fields of science, health and engineering, the IPBS is part of one of the most important scientific research poles in health and biological sciences in France. More informations... Staff 0 Research teams 0 CNRS International Actions 0 running European grants 0 Nationalities 0 M2 of laboratories 0 You wish to work on cancer, infectious or inflammatory diseases, with cutting-edge approaches in cellular, molecular and structural biology, in a rich and stimulating environment? Join us! READY TO COLLABORATE ? Get In Touch Contact us IPBS-Toulouse BP64182 205 route de Narbonne 31077 Toulouse Cedex04 News Intranet Extranet Legal...

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